Body entrance

Puncture or
catheterization for single flushing

Perfusion therapy for metastatic tumor of

ovarian cancer and bladder cancer

 

 

Based on the principle of tumor hyperthermia, using the external electromagnetic induction heating device of hyperthermic perfusion chemotherapy system, the treatment solution is continuously heated to the treatment temperature, introduced into the patient's body cavity through the power circulation pump, and the effective treatment temperature is maintained within 60 minutes to give full play to the thermal killing mechanism.Process thermal cleaning of metastatic cancer cells widely cultivated in serous, and add chemotherapy drugs with heat sensitization effect according to the characteristics such as metabolic block of cancer cells and damage of genetic material after HIPEC, to force cancer cells to stop dividing, eliminate lesions that causes malignant effusion , make rapid repair of the biofilm, and achieve the goal of effective treatments for cancer effusion.

 

Start

Establishing a
channel for
B-ultrasound
positioning

 

End of treatment

Clean drainage (surgery)
Retain an appropriate amount of residual fluid in the body
cavity (internal medicine)
End of treatment

Treatment of gastric cancer, lung cancer, colorectal cancer,

intraoperative and postoperative prevention and

treatment of implant metastasis

Perfusion therapy for cancer cells, metastatic nodules, and residual lesions that cannot be removed by surgery

Perfusion therapy for malignant body cavity effusion (chest, abdominal cavity)

 

Treatment of malignant thoracoperitoneal mesothelioma

 

Cardiovascular insufficiency

Body temperature above 38 degree C

 

Bleeding-prone diseases

 

Severe thoracic and abdominal adhesions

Poor patient compliance

Body exit

Puncture or catheterization — After replacing the accumulated liquid, enter the circulation mode
and preset the temperature — The entry
temperature reaches the treatment temperature, and chemotherapy drugs are added to maintain a
constant temperature — circulate perfusion for 60 minutes

 

Obvious

curative effect

 

No damage to physiological function and no adverse sequelae

 

 
 

Reduce the toxic and side effects of chemotherapy drugs in body

cavity

 

Lung adenocarcinoma hydrothorax:After one time pleural hyperthermic perfusion,hydrothorax can only be detected to scatter in masses of cancer cells.Most of the cancer cells have been degraded by apoptosis.

Pathological Picture

 

 
 

Tumor tissue biopsy:a cluster of cancer cells with variable size and morphology and darker staining before treatment.After thermal perfusion,the cancer cells disappeared.

 

1

Short treatment course

 

3 times of average treatment and 10 days

of average hospitalization

 

 

The control effective rate of cancerous effusion is significantly improved

2

Stable long-term effect

 

New means

 

The remission period is prolonged,the quality of life is significantly improved,and the recurrence rate is reduced

3

 
 

—— Clinical application of thermostatic circulatory hyperthermia perfusion chemotherapy in the prevention and treatment of body cavity metastatic cancer

 

4

Toxic side

effects

 

5

6

Good method for prevention and treatment of cancerous implantation metastasis and prevention of malignant peritoneal effusion

 

 
 

Clinical indications

Contraindication

 
 
 

Clinical Indications

 
 

A. Treatment of gastric cancer, lung cancer, colorectal cancer, intraoperative and postoperative prevention and treatment of implant metastasis

B. Perfusion therapy for cancer cells, metastatic nodules, and residual lesions that cannot be removed by surgery

C. Perfusion therapy for malignant body cavity effusion (chest, abdominal cavity)

D. Perfusion therapy for metastatic tumor of ovarian cancer and bladder cancer

E. Treatment of malignant thoracoperitoneal mesothelioma

 

Treatment Principle

 

 
 
 
 
 
 

Changes of hydrocele before and after one-time intracavitary

circulatory thermal perfusion

 

 

Graphical Description 

 

 
 
 

Ideal Practical Value Six Advantages

 

Sequela

 

Yellow

Bloody

Chylous

Jelly like

Excreted fibrous tissue

Excreted neoplasm nodules

 

Hyperthermic Perfusion Chemotherapy Equipment
Prevent and Treat Cancer Cell Implantation & Metastasis Control Peritoneal and Pleural Malignant Effusion
 
Clinical Indications
A.Adjuvant treatment for the prevention and treatment of implantation metastatic cancer during and after the operation of celomic malignancies such as lung cancer,gastric cancer,colorectal cancer,ovarian cancer and pancreatic cancer
B.Postoperative treatment of cancer cells,metastatic nodules,enlarged lymph nodes and residual small lesions that cannot be removed by surgery
C.Malignant body cavity effusion(pleural cavity,peritoneal cavity)
D.Treatment of pleuroperitoneal cavity diffuse metastatic tumor
E.Treatment of malignant pleuroperitoneal mesothelioma
 
GD
 
Treatment Principle
Based on the principle of tumor hyperthermia,using the external electromagnetic induction heating device of hyperthermic perfusion chemotherapy system,the treatment solution is continuously heated to the treatment temperature,introduced into the patient's body cavity through the power circulation pump,and the effective treatment temperature is maintained within 60 minutes to give full play to the thermal killing mechanism.Process thermal cleaning of metastatic cancer cells widely cultivated in serous,and add chemotherapy drugs with heat sensitization effect according to the characteristics such as metabolic block of cancer cells and damage of genetic material after HIPEC,to force cancer cells to stop dividing,eliminate lesions that causes malignant effusion,make rapid repair of the biofilm,and achieve the goal of effective treatments for cancer effusion.
 
Changes of hydrocele before and after one-time intracavitary circulatory thermal perfusion
GD
GD
GD
 
 
 
Yellow
Bloody
Chylous
 
 
 
GD
GD
GD
     
Jelly like
Excreted fibrous tissue
Excreted neoplasm nodules

 

Graphical Description

GD

 

Start:B ultrasound positioning
 
Body entrance:Puncture --One way perfusion
 
Body exit:Puncture or catheterization--replacement of effusion and then into circulation mode--preset temperature--chemotherapy drugs will be added when the body entrance temperature reaches the treatment temperature--maintain circulatory perfusion for 60 minutes at constant temperature
 
Keep appropriate amount of circulating fluid until the end of treatment:The end of treatment
 
Pathological Picture
 
GD
GD
   
Lung adenocarcinoma hydrothorax:After one time pleural hyperthermic perfusion,hydrothorax can only be detected to scatter in masses of cancer cells.Most of the cancer cells have been degraded by apoptosis.
   
GD
GD
   
Tumor tissue biopsy:a cluster of cancer cells with variable size and morphology and darker staining before treatment.After thermal perfusion,the cancer cells disappeared.
 
 
 
Ideal Practical Value Six Advantages
1.Short treatment course,3 times of average treatment and 10 days of average hospitalization
2.Obvious curative effect,The control effective rate of cancerous effusion is significantly improved
3.Stable long-term effect,The remission period is prolonged,the quality of life is significantly improved,and the recurrence rate is reduced
4.Sequela,No damage to physiological function and no adverse sequelae
5.Toxic side effects,Reduce the toxic and side effects of chemotherapy drugs in body cavity
6.New means,Good method for prevention and treatment of cancerous implantation metastasis and prevention of malignant peritoneal effusion
 
—— Clinical application of thermostatic circulatory hyperthermia perfusion chemotherapy in the prevention and treatment of body cavity metastatic cancer
 
Clinical indications
 ▼
Adjuvant therapy for prevention and treatment of implant metastasis of malignant tumors such as lung cancer,gastric cancer,intestinal cancer,ovarian cancer and pancreatic cancer during and after operation
Postoperative treatment of unresectable cancer cells, metastatic nodules, enlarged lymph nodes and residual small lesions
Malignant coelomic effusion (pleural, abdominal
Treatment of diffuse metastases in thoracic and abdominal cavity
Treatment of malignant pleuroperitoneal mesothelioma
 
Contraindication
 ▼
Cardiovascular insufficiency
Body temperature above 38 degree C
Bleeding-prone diseases
Severe thoracic and abdominal adhesions
Poor patient compliance